Nothing Sacred or Nothing's Sacred may refer to:

Film and television Nothing Sacred (film), a 1937 American screwball comedy Nothing Sacred (TV series), a 1997–1998 American drama series "Nothing Sacred" (Murder City), a 2004 television episode

Literature Nothing Sacred (novel), a 2010 novel by Boris Akunin Nothing Sacred (play), a 1988 play by George F. Walker adapted for a 1998 Canadian television film Nothing Sacred, a 2004 science fiction novel by Tom Flynn Nothing Sacred: The Truth About Judaism, a 2003 book by Douglas Rushkoff Nothing's Sacred (book), a 2005 autobiography by Lewis Black

Music Nothing Sacred (band), a 1980s heavy metal group Nothing Sacred (album), by David Allan Coe, 1978 Nothing's Sacred (album), by Lȧȧz Rockit, 1991 Nothing Sacred, an album by Babylon A.D., 1992 "Nothing Sacred – A Song for Kirsty", a song by Russell Watson, 2002 "Nothing Sacred", a song by Memento from Beginnings, 2003 "Nothing's Sacred", a song by London After Midnight from Violent Acts of Beauty, 2007

See also Is Nothing Sacred?, a 1983 album by the Lords of the New Church "Is Nothing Sacred", a 1999 song by Meat Loaf