BMP/retinoic acid-inducible neural-specific protein 1, also known as deleted in bladder cancer protein 1 (DBC1) is a protein that in humans is encoded by the BRINP1 gene.
This gene is located within chromosome 9 (9q32-33), a chromosomal region that frequently shows loss of heterozygosity in transitional cell carcinoma of the bladder. It contains a 5' CpG island that may be a frequent target of hypermethylation, and it may undergo hypermethylation-based silencing in some bladder cancers.
The functions of this gene are unknown, and it has not yet been placed in a protein family or functional pathway. Nonetheless, it is suspected to act as a tumor suppressor gene.
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