USS Bainbridge may refer to any of five warships named after the early U.S. Navy hero William Bainbridge:

, was a 12-gun brig commissioned in 1842 and lost off Cape Hatteras in 1863 , was the first destroyer of the US Navy, in service from 1902 to 1919 , was a destroyer, commissioned in 1920 and sold in 1945 , was commissioned as a nuclear-powered frigate and in service from 1962 to 1996. In 1975 during Naval reorganization, she was redesignated as a cruiser , is an guided missile destroyer, commissioned on 12 November 2005 and currently in service

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