TCU may refer to:
Education Taguig City University, a university in Metro Manila, Philippines Tanzania Commission for Universities, regulatory body for Universities in Tanzania Texas Christian University, a private university in Fort Worth, Texas TCU Horned Frogs, the athletic programs of the school Tokyo Christian University, a private university in Chiba, Japan Tokyo City University, a private university in Tokyo, Japan Tzu Chi University, a private university in Hualien, Taiwan Tianjin Chengjian University, a university in Tianjin, China Tribal colleges and universities
Science and technology Telecommunication control unit, a device that regulates input and output in a mainframe computer Telematic control unit, a device on board of a vehicle that controls tracking of the vehicle Transmission control unit, a controlling device in automobile transmissions and engines Thompson/Center Ugalde, a family of custom ammunition cartridges for firearms Towering cumulus cloud (TCu), types of which are cumulus congestus or cumulus castellanus
Other Tauranga City United, a New Zealand association football club Transitional care unit, a facility in a hospital where the level of care falls between intensive care and normal care Transportation Communications Union, a labor group for railroad-related workers Triangle Credit Union, a bank in New Hampshire Tribunal de Contas da União, the Brazilian federal court of accounts Turn construction unit, a segment of speech in the study of linguistics The Twisted Childhood Universe, a shared universe of horror films