SPF may refer to:
Science and technology
Sun protection factor, of sunscreen Space Power Facility, a NASA test facility
Biology Specific-pathogen-free, laboratory animals known to be without pathogens S-phase-promoting factor, in biology Spot 42 RNA, a small regulatory RNA found in some Gammaproteobacteria
Computing and mathematics Sender Policy Framework, for email authentication IBM Structured Programming Facility, later ISPF Shortest Path First, or Dijkstra's algorithm Formal spectrum of a ring, a construction in algebraic geometry
Materials Superplastic forming, of sheet metal Spray polyurethane foam, a building insulation material Spruce-pine-fir, mixed softwood timber
Government Social protection floor Security Policy Framework, UK , the Argentine Federal Penitentiary Service Scottish Police Federation, represents Scottish police officers Singapore Police Force Somali Police Force Special Police Force, a unit within a police force
Economics Survey of Professional Forecasters, US macroeconomic forecasts survey ECB Survey of Professional Forecasters, macroeconomic forecasts
Transportation Black Hills Airport (IATA airport code), South Dakota, US Sherwood Park Freeway, Edmonton, Alberta, Canada Springfield railway station (Scotland), station code Safety Performance Function, a predictive modeling type used in Road safety
Other uses Annual Summer Play Festival, New York City, US , the oldest poetry society in France (Conspiracy of Fire Nuclei), Greek terrorist organization
See also Single point of failure (SPOF) Socialist Party of Florida (SPFL)