RPO may refer to:
Business Recovery point objective, in business-continuity planning for computing Recruitment process outsourcing, a form of business-process outsourcing Regular Production Option, a General Motors standard coding system
Military Regulating Petty Officer, a rate (rank) in the Royal Navy Police RPO-A Shmel (Bumblebee), a grenade launcher produced by Russia
Music Rochester Philharmonic Orchestra, an orchestra in New York State Royal Philharmonic Orchestra, an orchestra in London, England
Science and technology Recursive path ordering, a well-ordering in term rewriting (computer science) Rendezvous and proximity operations, in spaceflight Research Performing Organisations, a term used in European science policy
Sports Runs per over or run rate, a measure in the game of cricket Run-pass option, an offensive scheme in American football
Other Railway post office, a mobile post office set up in a railway car Retail Post Outlet, a Canadian postal abbreviation Revenue Protection Officer, a UK railway employee who issues penalty fares Rzecznik Praw Obywatelskich, a Polish ombudsman