Izumo (出雲) may refer to:

Locations Izumo Province, an old province of Japan Izumo, Shimane, a city located in Shimane Prefecture Izumo Airport Izumo-taisha, one of Japan's most ancient and important Shinto shrines

Ships Izumo-class multi-purpose destroyer, a class of multi-purpose operation destroyer operated by the Japan Maritime Self-Defense Force JS Izumo, lead ship of this class Japanese cruiser Izumo, an armored cruiser operated by the Imperial Japanese Navy

Fiction SDF-4 Izumo, a spaceship in the Robotech universe Izumo: Takeki Tsurugi no Senki, an anime series Kunisaki Izumo no Jijō, a Japanese manga series Izumo Kamurogi, the commander of Altair forces in the anime series Aquarion Evol Daisuke Izumo, the main character in the anime series Ninja Captor

Other Izumo (train), a former train service in Japan Sunrise Izumo, a train service in Japan IZUMO1, a sperm-specific protein necessary for sperm-egg plasma membrane binding and fusion.