KE, ke, and variations may refer to:

Companies KE Holdings, a Chinese real estate broker Korean Air (IATA airline designator KE)

Language Ke (kana), the romanisation of the Japanese kana け and ケ Small ke (ヶ), a Japanese character, a small form of ke (ケ) Ke (Armenian letter)

People Ke (surname) (kē, 柯), a transliteration of a common Chinese surname Ké, stage name of New York singer/songwriter/actor Kevin Grivois

Places Kenya (ISO 3166 code KE) County Kildare, Ireland Košice, Slovakia

Science and technology Biology and medicine KE family, a family of Pakistani origin exhibiting a severe speech disorder Key Event, in toxicology, an element in an adverse outcome pathway Kinetic energy penetrator, a type of ammunition designed to penetrate vehicle armour Elimination rate constant, a value used to calculate the rate at which drugs are removed from the system Lithocarpus glaber, the Japanese oak, called "ke" in Chinese

Computing and the internet .ke, internet top-level domain for Kenya Knowledge engineering, in computer and cognitive sciences

Physics Coulomb constant (ke) Kinetic energy

Other uses Ke (unit), a traditional Chinese unit of time lasting 14.4 minutes or 15 minutes Operation Ke, the Japanese withdrawal from Guadalcanal in the Second World War The first generation Mazda CX-5 (model name KE)