William Woodruff (1916–2008) was a world historian and author.
William Woodruff may also refer to:
William E. Woodruff (politician) (1795–1885), American politician and publisher William E. Woodruff (soldier) (fl. 1855–1863), American lawyer and colonel in the Union Army during the American Civil War William Woodruff (Upper Canada politician) (1793–1860), Canadian merchant and politician