Piccinni is an Italian surname. Notable people with the surname include:
Niccolò Piccinni (1728–1800), Italian composer Teatro Piccinni, Italian theater in Bari, Apulia Louis Alexandre Piccinni (1779–1850), Italian-French composer, grandson of Niccolò
Notable people with the surname Piccini include: Achille Piccini (1911–1995), Italian football player Augusto Piccini (1854–1905), Italian chemist Cristiano Piccini (born 1992), Italian footballer, defender David Piccini (born 1988), Canadian politician Isabella Piccini (1664–1732), Italian nun and artist Teresa Piccini, Mexican ten-pin bowler who competed at the 2006 AMF World Cup
See also Picini, tribe of American woodpeckers of the subfamily Picinae