Arquà Polesine (; ) is a comune (municipality) in the Province of Rovigo in the Italian region Veneto, located about southwest of Venice and about southwest of Rovigo.
Arquà Polesine borders the following municipalities: Bosaro, Costa di Rovigo, Frassinelle Polesine, Polesella, Rovigo, Villamarzana.
Sights include the castle, built in 1146 by Guglielmo III degli Adelardi Marcheselli, lord of Ferrara, and the parish church (rebuilt around 1516).
Twin towns Arquà Polesine is twinned with:
Vourles, France.
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