Two ships of the United States Navy have been assigned the name USS Upshur, in honor of individuals whose last name was Upshur.

The first, , was a Wickes-class destroyer, launched in 1918 and struck in 1945 was named for Rear Admiral John Henry Upshur. The second, , was a Barrett-class troop ship named for Major General William P. Upshur, USMC.

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