Ralph Assheton may refer to:

Sir Ralph de Ashton or Assheton (fl. 1421–1486), 15th century nobleman, also known as 'The Black Knight' Ralph Assheton (died 1559), MP for Liverpool (UK Parliament constituency) Ralph Assheton (general) (1596–1650), MP for Lancashire Sir Ralph Assheton, 2nd Baronet, of Lever (c. 1605–1680), MP for Clitheroe Sir Ralph Assheton, 2nd Baronet, of Middleton (1652–1716), MP for Liverpool and Lancashire Ralph Assheton (1830–1907), MP for Clitheroe Sir Ralph Assheton, 1st Baronet (1860–1955) Ralph Assheton, 1st Baron Clitheroe (1901–1984), Conservative Party politician and MP Ralph Assheton, 2nd Baron Clitheroe (born 1929)

It may also refer to one of their many ancestors named Ralph Assheton: see Assheton baronets