HSL may refer to:
Science, technology and computing HSL (Fortran library), a numerical software library HSL and HSV color space Health and Safety Laboratory, UK Hormone-sensitive lipase, a protein Hybrid solar lighting
Transport Bell HSL, a 1950s U.S. Navy antisubmarine helicopter Haslemere railway station in England Helsinki Regional Transport Authority (), in Finland High-speed launch, a type of military boat typically used for air-sea rescue operations Hindustan Shipyard, in Visakhapatnam, Andhra Pradesh, India Hispania Líneas Aéreas, a defunct Spanish airline HSL Logistik, a German train operator Huslia Airport, in Alaska, US High-speed rail lines in Benelux HSL 1, HSL 2 HSL 3 HSL 4, and HSL-Zuid HSL-34 to HSL-94: Former US Navy helicopter Anti-submarine (Light) squadrons
Other uses Hausa Sign Language, Kano, Nigeria Hawaiʻi Sign Language, Hawaii, United States Hamburg School of Logistics, now Kühne Logistics University, Germany Staff Selection Commission Combined Higher Secondary Level Exam or CHSL/HSL, civil service examination by the Staff Selection Commission for governmental posts in India