Potosí or Potosi may refer to the following topics, whose names generally originate from the name of Potosí, a city in modern-day Bolivia that was the center of world silver production during the reign of the Spanish Empire:

Places United States Potosi, Missouri, in Washington County Potosi, Nevada, a ghost town in Clark County, Nevada Potosi, Texas, in Taylor County Potosi (town), Wisconsin, in Grant County Potosi, Wisconsin, a village within the Town of Potosi

Elsewhere Potosí, the capital of Potosí Department, Bolivia, a silver mining center and UNESCO World Heritage Site Potosí Department, a department in southwestern Bolivia Potosí, Nicaragua, a town in Rivas Department Potosi, Venezuela, a disestablished town in Táchira San Luis Potosí City, capital and most populous city of San Luis Potosí, Mexico

Mountains Potosi Mountain (Nevada), U.S. Potosí mountain range or Cordillera de Potosí, to the southeast of the city of Potosí, Bolivia Potosi Peak, in the Sneffels Range, Colorado, US Cerro de Potosí, a mountain near the city of Potosí, Bolivia, also known as Cerro Rico; a Spanish colonial mining site Cerro Potosí, a mountain in Nuevo León, Mexico Huayna Potosí, a mountain in the La Paz Department, Bolivia Wayna Potosí (Oruro), a mountain in the Oruro Department, Bolivia

Other uses Potosi (barque), an 1895 German sailing ship named after the Bolivian city Potosi Correctional Center, a prison near Potosi, Missouri Potosi Mining District, in Clark County, Nevada Potosi, Trelawny, Jamaica, a former sugar plantation Potosi Pinyon (Pinus culminicola), a species of pine tree native to northeast Mexico Potosi pupfish (Cyprinodon alvarezi), a species of fish once endemic to Mexico, but now extinct in the wild

See also Potosi Mine (disambiguation) Potosi Mountain (disambiguation)