Pestilence may refer to:

Infectious disease Pestilence, one of the Four Horsemen of the Apocalypse Pestilence (band), a Dutch death metal group Pestilence (comics), a Marvel Comics supervillain, based on the biblical horseman "Pestilence" (Medici: Masters of Florence), a television episode "The Pestilence", a song by Kreator from Pleasure to Kill "The Pestilence" is another name for the Black Death.

See also Pestilence wort, a perennial plant native to Europe and northern Asia :Category:Plague gods Pest (disambiguation)